Figure 5
From: High-dose exposure to butylparaben impairs thyroid ultrastructure and function in rats
BuP inhibited the level of sodium/iodide symporter (NIS) in rat thyroid and human thyroid cell lines. (A) In vivo, BuP exposure caused a decrease in NIS in rats compared to the control group. (B) In vitro, BuP inhibited the level of NIS in Nyth-ori3-1, a human thyroid epithelial cell line, in a concentration-dependent manner. n = 3, data are expressed as mean ± SD. Compared with control group, * P < 0.05, ***P < 0.001.
