Figure 7
From: High-dose exposure to butylparaben impairs thyroid ultrastructure and function in rats
BuP induced apoptosis and impaired the anti-apoptosis ability of thyroid epithelial cells. (A) BuP increased the level of cleaved caspase-3, indicating that it promoted apoptosis of thyroid follicular cells. n = 5. (B) BuP decreased the level of Bcl-2 and increased the level of Bax, resulting in a decrease in the ratio of Bcl-2/Bax, indicating that BuP decreased the anti-apoptotic ability of thyroid follicular cells. n = 4, data are expressed as mean ± SD. Compared with control group, * P < 0.05, **P < 0.01, ***P < 0.001.
