Table 2 Associations of the groups with markers of spiroergometry compared to SHIP controls.

From: Metabolic cost of unloading pedalling in different groups of patients with pulmonary hypertension and volunteers

 

CTEPH β (95%-CI)

HFpEF β (95%-CI)

IPAH β (95%-CI)

PAH-CTD β (95%-CI)

Patient controls β (95%-CI)

SHIP controls

VO2 (ml/min) at rest

67.2 (53.0; 81.4)*

62.1 (49.2; 75.1)*

53.9 (39.1; 68.7)*

73.1 (58.4; 87.8)*

43.7 (29.8; 57.6)*

Reference

VO2 (ml/min) at unloading exercise

 − 56.0 (− 77.2; − 34.7)*

 − 58.6 (− 78.0; − 39.2)*

 − 84.6 (− 107; − 62.5)*

 − 49.7 (− 71.7; − 27.7)*

 − 44.4 (− 65.3; − 23.6)*

Reference

VO2 (ml/min) at peak

 − 760 (− 848; − 672)*

 − 688 (− 769; − 608)*

 − 985 (− 1077; − 893)*

 − 737 (− 828; − 645)*

 − 594 (− 681; − 508)*

Reference

Internal work (IW) (ml/min)

 − 121 (− 138; − 104)*

 − 119 (− 135; − 103)*

 − 136 (− 154; − 118)*

 − 121 (− 139; − 104)*

 − 86.3 (− 103; − 69.5)*

Reference

Proportional IW (%)

 − 1.92 (− 3.09; − 0.75)*

 − 1.98 (− 3.05; − 0.91)*

0.02 (− 1.20; 1.23)

 − 1.61 (− 2.82; − 0.39)*

 − 0.25 (− 1.39; 0.90)

Reference

Internal work (IW) (Watt)

 − 8.31 (− 10.3; − 6.35)*

 − 10.5 (− 12.3; − 8.70)*

 − 7.78 (− 9.81; − 5.74)*

 − 6.81 (− 8.84; − 4.78)*

 − 7.10 (− 9.02; − 5.18)*

Reference

Proportional IW (IW/Wattmax in %)

1.08 (− 1.06; 3.22)

 − 0.85 (− 2.80; 1.11)

5.77 (3.55; 8.00)*

3.70 (1.47; 5.93)*

1.92 (− 0.16; 4.02)

Reference

  1. Coefficients are derived from linear regression models adjusted for age, sex, and body mass index.
  2. CI confidence interval; *p < 0.05.
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