Figure 1
From: HSPA9 reduction exacerbates symptoms and cell death in DSS-Induced inflammatory colitis
Diminished HSPA9 expression in inflammatory bowel Disease (IBD). (A–C) Comparative analysis of HSPA9 expression in human samples from patients with IBD using the Gene Expression Omnibus (GEO) on the National Center for Biotechnology Information (NCBI) website. (A) HSPA9 expression in colonic mucosa samples from patients with ulcerative colitis (UC) compared with controls from GEO datasets (GDS) 3119. (B) Examination of HSPA9 expression in peripheral blood mononuclear cells from patients with UC, patients with Crohn’s disease (CD), and healthy controls. (C) Comparison of HSPA9 expression in intestinal biopsies from twin pairs, where one individual is healthy and the other has UC. Data are presented as the mean ± standard deviation. Statistical significance was determined using an ordinary one-way ANOVA. *p < 0.01, **p < 0.005, and ***p < 0.0001.
