Figure 6

Diagnostic marker genes selection. (A) The performance in of ten-time cross-verification for tuning parameter in selection LASSO. (B,C) Biomarker signature gene expression validation by support vector machine recursive feature elimination (SVM–RFE) algorithm selection. (D) randomForest error rate versus the number of classification trees. (E) The top 50 relatively important genes. (F) Venn plot shows the key genes screened by three machine learning methods.