Figure 4 | Scientific Reports

Figure 4

From: Nuciferine reduces vascular leakage and improves cardiac function in acute myocardial infarction by regulating the PI3K/AKT pathway

Figure 4

Nuciferine reduces leakage and maintains the stability of vascular endothelial AJs. (A, B) Western blotting was performed to detect the effect of nuciferine on the expression of intracellular Ve-cadherin in HCMECs. n = 4. (C) Transwell assay was performed to detect the permeability of HCMECs. n = 4. (D) Representative images of Ve-cadherin immunofluorescence staining of HCMECs under each of the indicated experimental conditions. n = 4. Scale bar = 10 μm. (E) Quantitative analysis of the intracellular Ve-cadherin fluorescence intensity. n = 4. Data are expressed as the mean ± SD. NS, No significance (P > 0.05); *P < 0.05, **P < 0.01, ***P < 0.001 vs. Ctrl group.

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