Table 2 Outcome data and complications during extracorporeal cardiopulmonary resuscitation among each group.

From: Impact of center volume on in-hospital mortality in adult patients with out‑of‑hospital cardiac arrest resuscitated using extracorporeal cardiopulmonary resuscitation: a secondary analysis of the SAVE-J II study

Variables

HVC (n = 629)

MVC (n = 510)

LVC (n = 601)

P value

ECPR or ECMO management complications

 Overalla

175 (27.8%)

141 (37.6%)

209 (34. 8%)

0.010

Procedure related complications

 Cannula malposition

10 (1.6%)

44 (8.6%)

30 (5.0%)

 < 0.001

 Unsuccessful cannulation

3 (0.5%)

6 (1.2%)

4 (0.7%)

0.381

 Cannulation related bleeding

89 (14.2%)

72 (14.2%)

92 (15.4%)

0.794

 Others

23 (3.7%)

26 (5.1%)

24 (4.0%)

0.469

ECMO management related complications

 Hemorrhage

44 (7.0%)

26 (5.1%)

76 (12.8%)

 < 0.001

 Ischemia

14 (2.2%)

7 (1.4%)

10 (1.7%)

0.536

 ECMO equipment trouble

4 (0.6%)

3 (0.6%)

22 (3.8%)

 < 0.001

 Others

11 (1.8%)

7 (1.4%)

5 (0.9%)

0.393

Outcomes

 Survival to hospital discharge, n (%)

210 (33.4%)

123 (24.1%)

161 (26.8%)

0.001

 Favorable neurological outcome, n (%)

105 (16.7%)

62 (12.2%)

95 (15.8%)

0.085

 Length of ECMO, days

4 (3, 5)

3 (2, 5)

3 (2, 5)

0.260

 Length of hospital stay, days

5 (2, 25)

2 (1, 12)

4 (2, 23)

 < 0.001

 Length of hospital stay among survivors, days

32 (22, 53)

30 (26, 44)

40 (28, 60)

 < 0.001

  1. Data are presented as the median [interquartile range], or n (%). HVC high-volume center, MVC medium-volume center, LVC low-volume center, ECMO extracorporeal membrane oxygenation.
  2. aPercentage of patients with complications (even if two or more complications, count as one).