Table 1 Patient characteristics categorized by MTBC genotypes originally infecting the investigated patients.
From: Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania
Characteristics | All participants (n = 28) | Lineage 1.1.2 (n = 6) | Lineage 2.2.1 (n = 8) | Lineage 3.1.1 (n = 8) | Lineage 4.3 (n = 6) |
|---|---|---|---|---|---|
Age in years, median (IQR) | 24 (21–34) | 37 (27–42) | 24 (23–30) | 22 (19–24) | 25 (21–32) |
Age group in years, n (%) | |||||
18–24 | 16 (57) | 2 (33) | 5 (62.5) | 6 (75) | 3 (50) |
25–34 | 5 (18) | 0 | 1 (12.5) | 3 (25) | 2 (33) |
35–44 | 4 (14) | 3 (50) | 1 (12.5) | 0 | 0 |
≥ 45 | 3 (11) | 1 (17) | 1 (12.5) | 0 | 1 (17) |
Male, n (%) | 23 (82) | 6 (100) | 8 (100) | 5 (62.5) | 4 (67) |
BMI, kg/m2, median (IQR) | 18.1 (16.7–19.9) | 16.5 (16.4–17) | 18.9 (18.1–20.4) | 18.6 (17.7–20.2) | 17.3 (16.8–18.3) |
Symptoms, n (%) | |||||
Cough | 28 (100) | 6 (100) | 8 (100) | 8 (100) | 6 (100) |
Fever | 19 (68) | 4 (66.7) | 3 (37.5) | 6 (75) | 6 (100) |
Night sweat | 19 (68) | 4(66.7) | 5 (62.5) | 5 (62.5) | 5 (83) |
Significant weight loss | 23 (82) | 6 (100) | 5 (62.5) | 6 (75) | 6 (100) |
TB patient category, n (%) | |||||
New | 25 (89) | 5 (83.3) | 6 (75) | 8 (100) | 6 (100) |
Relapse | 2 (7) | 1 (16.7) | 1 (12.5) | 0 | 0 |
Treatment after default | 1 (4) | 0 | 1 (12.5) | 0 | 0 |
Full blood counts (109 cells/L) | |||||
White Blood cells, median (IQR) | 6.6 (5.7–7.7) | 6.8 (5.6–7.5) | 6.3 (5.5–7.2) | 6.9 (5.97–7.50) | 6.2 (5.46–8.34) |
Platelets, median (IQR) | 319 (264–449) | 368 (267–423) | 316 (275–484) | 299 (280–448) | 324 (261–363) |
Red blood cells, mean (± SD) | 5.0 (0.8) | 4.8 (0.7) | 5.1 (0.8) | 4.8 (0.6) | 5.5 (1.2) |
Xpert, Ct value, median (IQR) | 19.6 (15.4–23.5) | 18.4 (15.0–22.9) | 19.6(15.2–19.9) | 19.8 (16.8–24.3) | 19.4 (16.8–23.1) |
Culture results, n (%) | |||||
Scanty | 3 (11) | 1 (16.7) | 1 (12.5) | 0 | 1 (16.7) |
1+ | 18 (64) | 2 (33.3) | 5 (62.5) | 7 (87.5) | 4 (66.6) |
2+ | 6 (21) | 2 (33.3) | 2 (25) | 1 (12.5) | 1 (16.7) |
3+ | 1 (4) | 1 (16.7) | 0 | 0 | na |
