Figure 3 | Scientific Reports

Figure 3

From: Exercise ameliorates muscular excessive mitochondrial fission, insulin resistance and inflammation in diabetic rats via irisin/AMPK activation

Figure 3

Exercise improves morphology and inflammation of skeletal muscle in diabetic rats. (A) H&E staining of representative Skeletal muscle sections. (B) Weight of soleus muscle. (C–E) Immunofluorescence and its semiquantitative analysis for evaluating IL-1β and TNF-α expression in soleus muscle of rats between groups. (F–G) Western blot analysis of IL-1β and TNF-α expression in soleus muscle of rats between groups. Con control, DM Type 2 diabetes, Ex Type 2 diabetes combined with exercise, IL-1β interleukin-1β, TNF-α tumor necrosis factor-α. *Denotes the significant difference compared with Con group (p < 0.05); #indicates the significant difference compared with DM group (p < 0.05).

Back to article page