Table 2 Baseline characteristics of pregnancies according to diagnosis of LR asymmetry disorders.

From: Increased risk of fetal left–right asymmetry disorders associated with maternal SARS-CoV-2 infection during the first trimester

Characteristic

LR asymmetry disorders Fetuses

(n = 30)

Normal Fetuses

(n = 30)

P

Maternal Age

28.93 ± 4.91

30.97 ± 4.91

0.11

GA of confirmed LR asymmetry disorders

22.3 ± 4.2

22.33 ± 4.37

0.98

Previous pregnancies

  

0.19

None

16/30(53.33%)

12/30(40%)

 

1–2

9/30(30%)

16/30(53.33%)

 

3 + 

5/30(16.67%)

2/30(6.67%)

 

SARS-CoV-2

  

0.026*

Negative

1/30(3.33%)

8/30(26.67%)

 

Positive

29/30(96.67%)

22/30(73.33%)

 

Symptoms

   

Fever

28/29(96.55%)

21/22(95.45%)

1.0

Asthenia

11/29(37.93%)

7/22(31.81%)

0.77

Dyspnea

0

0

-

Cough

20/29(68.97%)

9/22(40.91%)

0.05

HNT symptoms

17/29(58.62%)

11/22(50%)

0.58

Headache

12/29(41.38%)

5/22(22.73%)

0.23

Myalgia

17/29(58.62%)

10/22(45.45%)

0.41

Trimester of infection

  

0.008*

I

28/29(96.55%)

15/22(68.18%)

 

II

1/29(3.45%)

3/22(13.64%)

 

III

0

4/22(18.18%)

 

Vaccination completed

  

0.68

None

6/30(20%)

4/30(13.33%)

 

1

2/30(6.67%)

1/30(3.33%)

 

2

3/30(10%)

6/30(20%)

 

3

19/30(63.33%)

19/30(63.33%)

 

Chromosome

  

1.0

Normal

29/30(96.67%)

30/30(100%)

 

Abnormal

1/30(3.33%)

0

 

Family History

  

–

Yes

0

0

 

No

30/30(100%)

30/30(100%)

 
  1. LR, left–right ;GA, gestational age; HNT = head, nose, throat.
  2. Significant values are in bold.