Table 1 Demographic and clinical characteristics of the patients included in this study, classified by their ICU stay outcome 18.

From: Serum cytokine dysregulation signatures associated with COVID-19 outcomes in high mortality intensive care unit cohorts across pandemic waves and variants

 

ICU non-survival (n = 38)

ICU survival (n = 16)

Non-ICU symptomatic (n = 16)

ρ between non-survival and survival groups

Demographic characteristics

Female %

31.58

25

25

nsa

Age in years (Mean ± SD)

71 ± 9.87

64 ± 10.15

70 ± 14.25

0.023b

Sample per patient

1.87 ± 0.93

1.94 ± 0.93

1

nsc

Clinical characteristics

PaO2/FiO2 at ICU admission (Median, p25-p75)

93 (83.5–109.8)

159.5 (128–191.8)

 < 0.0001c

SOFA score at admission (Median, p25-p75)

7 (6–9)

4.5 (3.25–5)

 < 0.0001c

APACHE II score at admission (Median, p25-p75)

16 (15–22)

10.5 (8.25–13)

 < 0.0001c

SARS-CoV-2 Immunization started (%)

0

0

6.25

nsa

Comorbidities

    

Coronary heart disease (%)

23.68

12.5

18.75

nsa

Hypertension (%)

76.32

68.75

62.5

nsa

Diabetes (%)

39.47

18.75

25

nsa

Obesity (%)

26.32

43.75

12.5

nsa

Cancer (%)

5.26

12.5

12.5

nsa

Chronic respiratory disease (%)

15.79

18.75

6.25

nsa

Immunosuppression (%)

2.63

0

0

nsa

Number of comorbidities (Median, p25-p75)

2 (1–3)

2 (1–2.75)

1 (0–2.75)

nsc

  1. ns = non-significant.
  2. aCalculated by Fisher’s exact test.
  3. bCalculated by unpaired t test with Welch’s correction.
  4. cCalculated by Mann–Whitney test.