Table 3 Linear association between thyroid hormone levels and cardiac structure indices.

From: The association between TSH and thyroid hormones in the normal or subclinical dysfunction range with left ventricular diastolic dysfunction

 

TSH

FT4

T3

Standardized β

P value

Standardized β

P value

Standardized β

P value

LAVI

Unadjusted

0.001

0.999

− 0.032

 < 0.001

− 0.045

 < 0.001

Model 1

0.016

0.007

0.011

0.077

− 0.033

 < 0.001

Model 2

0.015

0.016

0.012

0.057

− 0.041

 < 0.001

LVMI

Unadjusted

− 0.033

 < 0.001

− 0.056

 < 0.001

− 0.054

 < 0.001

Model 1

− 0.021

0.003

− 0.044

 < 0.001

− 0.046

 < 0.001

Model 2

− 0.021

0.003

− 0.044

 < 0.001

− 0.058

 < 0.001

LVIDd

Unadjusted

0.044

 < 0.001

− 0.003

0.597

− 0.049

 < 0.001

Model 1

0.012

0.040

− 0.049

 < 0.001

− 0.054

 < 0.001

Model 2

0.014

0.016

− 0.041

 < 0.001

− 0.067

 < 0.001

LVPWd

Unadjusted

0.016

0.012

− 0.008

0.214

− 0.006

0.314

Model 1

0.023

 < 0.001

− 0.017

0.008

− 0.007

0.280

Model 2

0.015

0.015

− 0.011

0.077

− 0.005

0.393

RWT

Unadjusted

0.022

 < 0.001

− 0.015

0.015

− 0.007

0.225

Model 1

0.025

 < 0.001

− 0.019

0.002

− 0.008

0.211

Model 2

0.017

0.006

− 0.014

0.023

− 0.004

0.513

IVSd

Unadjusted

− 0.036

 < 0.001

0.020

0.002

0.008

0.173

Model 1

− 0.009

0.140

− 0.006

0.351

0.011

0.066

Model 2

− 0.009

0.099

− 0.002

0.759

− 0.008

0.149

  1. Model 1 was adjusted for age and sex.
  2. Model 2 was adjusted for age, sex, body mass index, hypertension, diabetes, dyslipidemia, and current smoking status.
  3. LAVI left atrial volume index, LVMI left ventricular mass index, LVIDd left ventricular internal diameter at diastole, LVPWd left ventricular posterior wall thickness at end-diastole, RWT relative wall thickness, IVSd diastolic interventricular septum, TSH thyroid-stimulating hormone, FT4 free thyroxine, T3 triiodothyronine.
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