Figure 1
From: Cluster effect for SNP–SNP interaction pairs for predicting complex traits

Summary of study design in the 2 study parts. (a) Simulation setting in Part 1: A cluster with 7 pairs: one causal (C–C) pair, and 6 with null (C–N) pairs. (b) Hybrid setting in Part 2: A cluster with 601 pairs: one observed causal pair and 600 simulated null pairs. MAF minor allele frequency, “C” represents a SNP from a causal pair; “N” represents a simulated null SNP.