Figure 3

Tumor-immunity cycle and immunotherapy response variation among CDR clusters. (A) Expression of leukocyte antigens, immune co-inhibitors and co-stimulators in CDR clusters. (B) Cancer-immunity circle difference. (C–D) Immune scores of CDR clusters using TIDE, MCPCounter, CIBERSORT, CIBERSORTx, ssGSEA. (*, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001; ns, P > 0.05).