Figure 6 | Scientific Reports

Figure 6

From: Pan-cell death-related signature reveals tumor immune microenvironment and optimizes personalized therapy alternations in lung adenocarcinoma

Figure 6

Construction of CDRSig. (A) Volcano plot for the up-regulated genes in CDR C4 and down-regulated genes in CDR C0. (B) LASSO COX regression analysis for DEGs in CDR C0 and C4. (C) Multivariate COX analysis of 8 genes in the CDRSig with the overall survival. (D) Survival curve for the training and test samples stratified by CDI. (E) Time-dependent ROC curve for TCGA training and test sets. (F) Overview of association among CDI, prognosis and 8 genes expression from CDRSig in training or test set. (G) Identification of CDI in CDR clusters. H, histogram of correlation between CDI and immune score. I, verification of RT/immune-related function analysis in CDI. (*, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001; ns, P > 0.05).

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