Figure 4 | Scientific Reports

Figure 4

From: Integrating plasma proteomics with genome-wide association data to identify novel drug targets for inflammatory bowel disease

Figure 4

Genetic colocalization of IBD (A-E), UC (F–H) and CD (I-J) (A) ERAP2 (B) RIPK2 (C) TALDO1 (D) CADM2 (E) RHOC (F) HGFAC (G) VSIR (H) CADM2 (I) MST1 (J) FLRT3. In this view, each dot is a genetic variant. The SNP with the most notable P value with IBD, UC and CD is marked, and the colors of other SNPs depends on the digit size ordering of linkage disequilibrium (r2). SNPs with missing linkage disequilibrium information are also coded dark blue. In the LocusZoom plots, -log10 (P.gwas) for links with IBD, UC and CD risk are on the x-axes, and -log10 (P.pqtl) for relationship with the protein levels on the y-axes.

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