Figure 1

SDS-PAGE analysis of urine samples from different diseases. (A) A distinct band between 15 and 25 kDa was highly expressed in pMHTN patients (M1–3) compared to other renal diseases. (B) SDS-PAGE analysis involving pMHTN, non-renal DCs, and HCs revealed that the specific band was present in 4 out of 5 pMHTN patients (M4, 5, 6, 8), while it was absent in DCs and HCs.M1-M8: pMHTN; DC 1–3: membranous nephropathy; DC 4–5: lupus nephritis, DC 6–8: IgA nephropathy; DC 9–11: IgA vasculitis; DC12-15: diabetes mellitus; DC 16–17: hypertension; DC 18–19: Behcet’s disease; HC 1–5: Healthy control. The gel images were cropped for clarity and the full-length gels are presented in Supplementary Materials.