Figure 2

Differentially expressed genes in four interstitial cystitis rat models. Volcano plots of upregulated and downregulated differentially expressed genes in (A) HCL, (B) AA, (C) PS + LPS, and (D) CYP models, respectively (n = 3). The x-axis represents a relative expression fold change of Log2 fold compared to the controls, and the y-axis indicates the threshold of a − Log10 p value. The red and blue points in the top right and top left sections show significantly upregulated and downregulated genes, respectively. Common (E) upregulated and (F) downregulated differentially expressed genes in four interstitial cystitis rat models.