Figure 2 | Scientific Reports

Figure 2

From: Analysis of the susceptibility of refractory hepatitis C virus resistant to nonstructural 5A inhibitors

Figure 2

Susceptibility of HCV 1B-4 strain and its derivatives with NS5A RASs to NS5A inhibitors. We seeded 1.5 × 104 cells/well in a 24-well plate; after 24 h of culture, anti-HCV agents were added and treated for 72 h. Susceptibility to NS5A inhibitors: (a) daclatasvir, (b) ledipasvir, (c) velpatasvir, (d) elbasvir, and (e) pibrentasvir was analyzed using the Renilla luciferase assay. NS nonstructural, HCV hepatitis C virus, RAS resistance-associated substitution.

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