Figure 1 | Scientific Reports

Figure 1

From: JNJ-77242113, a highly potent, selective peptide targeting the IL-23 receptor, provides robust IL-23 pathway inhibition upon oral dosing in rats and humans

Figure 1

Chemical structure of JNJ-77242113 (S3,1,S3,6-cyclo[N-acetyl-3-sulfanyl-L-valyl-L-asparaginyl-L-threonyl-7-methyl-L-tryptophyl-N6-acetyl-L-lysyl-3-sulfanyl-L-valyl-O-(2-aminoethyl)-L-tyrosyl-3-(naphthalen-2-yl)-L-alanyl-4-aminooxan-4-carbonyl-L-α-glutamyl-L-asparaginyl-3-(pyridin-3-yl)-L-alanyl-N2-methylglycinamide]).

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