Figure 6 | Scientific Reports

Figure 6

From: Icariin alleviates cisplatin-induced premature ovarian failure by inhibiting ferroptosis through activation of the Nrf2/ARE pathway

Figure 6

ICA rescued cis-induced apoptosis in KGN cells. (A,B) Determination of γH2AX and Bax protein expression levels in KGN cells from different treatment groups by WB (A) and quantitative analysis (B,C). (D,E), Effect of ICA on the percentage of Cis-induced apoptosis in KGN cells using Annexin V/PI staining and flow cytometry. (F,G), Effect of ICA and Fer-1 on the percentage of RSL3-induced apoptosis in KGN cells using Annexin V/PI staining and flow cytometry. Data are presented as mean ± SEM, **P < 0.01, ****P < 0.0001, ns, non-statistically significant.

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