Figure 5 | Scientific Reports

Figure 5

From: Integrated genomic/epigenomic analysis stratifies subtypes of clear cell ovarian carcinoma, highlighting their cellular origin

Figure 5

Integration of genomic and epigenomic features stratifies CCOC subtypes. (A) Five CCOC subtypes were distinguished based on DNA methylation-based clusters, the status of three driver genes (ARID1A, PIK3CA, and TP53), and mutational signatures. (B) Proposed evolutionary tree of CCOC according to methylation profiling, SWI/SNF status, and mutational signatures.

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