Figure 1 | Scientific Reports

Figure 1

From: Integrating network pharmacology with pharmacological research to elucidate the mechanism of modified Gegen Qinlian Decoction in treating porcine epidemic diarrhea

Figure 1

The effects of MGQD on immunosuppression. (a) Flow chart of the mouse immunodeficiency model. The red circular dots represent the weighing time nodes (i.e., the 1st, 4th, and 11th days), fasting for 12 h before weighing and drinking freely. (b) Three mice were randomly selected from the C and M groups for dissection after the completion of the model treatment. The thymus and spleen of group M mice showed significant atrophy. thymus index (mg/g) = thymus weight (mg)/ weight (g); spleen index (mg/g) = thymus weight (mg) /weight (g). (c) Comparison of body weight before and after modeling and after medication in each group. Gain weight (g) = body weight after medication (g)—body weight after modeling. (d, e) All experimental mice were dissected after the medication was completed. *P < 0.05, **P < 0.01, ***P < 0.001. (f, g) Histopathological changes in thymus and spleen in immunosuppressed mice. C: blank control group, M: cyclophosphamide (CTX)-induced model group, MGQD: MGQD treatment group.

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