Table 5 Summary of the amount of 64Cu radioactivity and NOTA-B11-antibody fragments used in the chelation reactions.
Antibody fragment type | 64Cu radioactivity in chelation reaction | Amount of NOTA-B11-antibody fragment in a chelation reaction (µg) | Amount of NOTA-B11-antibody fragment in a chelation reaction (nmol) | |
---|---|---|---|---|
µCi | MBq | |||
B11-diabody | 522.00 ± 6.24 (n = 3) | 19.31 ± 0.23 (n = 3) | 20 (n = 3) | 0.4 (n = 3) |
B11-scFv | 514.75 ± 17.74 (n = 4) | 19.31 ± 0.46 (n = 4) | 20 (n = 4) | 0.50 ± 0.20 (n = 4) |
B11-nanobody | 616.75 ± 324.22 (n = 4) | 22.82 ± 12 (n = 4) | 40 (n = 4) | 2.67 (n = 4) |