Fig. 4
From: BUB1 induces AKT/mTOR pathway activity to promote EMT induction in human small cell lung cancer

BUB1 knockdown impairs SCLC cell invasive and migratory activity. (A) In a wound healing assay, BUB1 silencing resulted in the significant impairment of SCLC cell migratory activity. (B) The silencing of BUB1 inhibited the migration of SCLC cells on gelatin, as shown through the quantification of 3D migration assay data. (C) Transwell invasion assays and corresponding quantification.