Fig. 4

Differentially expressed genes and enrichment analysis between ATC and normal tissues based on the GSE65144 dataset. A-B: Volcano map (A) and heatmap (B) of differentially expressed genes was constructed on normal and ATC group. (C) The most significantly enriched terms for GSE65144 were Herpes simplex virus 1 infection, cytokine–cytokine receptor interaction, extracellular structure organization, and extracellular matrix organization, and neutrophil degranulation, neutrophil activation involved in immune response.