Fig. 4 | Scientific Reports

Fig. 4

From: YTHDF1-regulated ALOX5 in retinal pigment epithelial cells under hypoxia enhances VEGF expression and promotes viability, migration, and angiogenesis of vascular endothelial cells

Fig. 4

ALOX5 regulates viability and migration of HUVECs. (A and B) ARPE-19 cells were transfected by shALOX5 or shNC lentiviral vector before hypoxia exposure and then the CM was collected and used to culture HUVECs. After 24 h, CCK-8 cell viability assay (A) and transwell migration assay (B) were performed in treated HUVECs. *P < 0.05, **P < 0.01, ***P < 0.001.

Back to article page