Fig. 5

ALOX5 affects angiogenesis of CAM. On embryonic day 7, the CM derived from shNC- (shNC-ARPE-19-CM) or shALOX5-transfected (shALOX5-ARPE-19-CM) ARPE-19 cells under hypoxia was carefully added on the CAM surface and incubation was then performed for 48 h. Images were captured and total length of formed vessels was gauged. *P < 0.05.