Fig. 5  | Scientific Reports

Fig. 5 

From: Squalene monooxygenase (SQLE) protects ovarian cancer cells from ferroptosis

Fig. 5 

SQLE knockdown increased the sensitivity of ovarian cancer cells to ferroptosis inducers, whereas SQLE overexpression decreased the sensitivity of ovarian cancer cells to ferroptosis inducers. (A) flow cytometric analysis detected changes in lipid peroxide levels in OC cells treated with ferroptosis inducer, (B) protein imprint assay detected GPX4 protein expression in OC cells treated with ferroptosis inducer, and (C) cell immunofluorescence assay detected protein expression levels of GPX4 in OC cells treated with ferroptosis inducer.

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