Fig. 4 | Scientific Reports

Fig. 4

From: Helicobacter pylori CagA mediated mitophagy to attenuate the NLRP3 inflammasome activation and enhance the survival of infected cells

Fig. 4

Mitophagy-related proteins expression were increased in gastric tissues of H. pylori infected mice. C57BL/6 mice were inoculated orally with the GZ7/cagA and GZ7/ΔcagA for 3 months, respectively. (A) H. pylori colonization status was detected by immunohistochemical staining; (B) Gastric tissues were collected and the expression of P62, LC3, PINK1 and PARKIN were detected by immunochemistry, Scale bar: 100 μm. The figure presents the average of three independent experiments. Data are presented as the means ± SD. Error bars represent the standard deviation. control, the uninfected cells; GZ7/ΔcagA, the GZ7/ΔcagA strains infected cells; GZ7/cagA, the GZ7/cagA strains infected cells; *p < 0.05, **p < 0.01; GZ7/cagA vs control, GZ7/cagA vs GZ7/ΔcagA.

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