Fig. 2 | Scientific Reports

Fig. 2

From: Heterogeneous expression of the atypical chemokine receptor ACKR3 in glioblastoma patient-derived tissue samples and cell cultures

Fig. 2

ACKR3 is expressed in different patterns in human glioma tissue and non-tumor brain tissue. (A) In blue, ACKR3 expression in GBM, Low Grade Glioma (LGG), Colon Adenocarcinoma (COAD), Acute Myeloid Leukemia (LAML), Skin Cutaneous Melanoma (SKCM) and Lung adenocarcinoma (LUAD) (TCGA data) vs. in grey, non-tumoral samples (GTEx data, using GEPIA tool in TCGA database). (B) Immunofluorescent staining of ACKR3 (green) in glioma patient FFPE tissue. White arrow indicates ACKR3 expression patterns. (C) ACKR3 immunofluorescent staining (green) in various regions of non-tumoral FFRE brain tissue: subventricular zone (SVZ), hippocampus (HIPPO), and cortex. of non-tumoral FFPE brain tissue. DAPI (blue) was used to counterstain nuclei. Scale bar = 10 μm.

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