Fig. 3 | Scientific Reports

Fig. 3

From: Immunogenic cell death signatures from on-treatment tumor specimens predict immune checkpoint therapy response in metastatic melanoma

Fig. 3

(A) Heatmap representing the single sample gene set enrichment analysis value of on-treatment NR and R in the Riaz et al. cohort. (B) The response rates of the low ICDS group and the high ICDS group for on-treatment samples from the Riaz et al. cohort. (C) Boxplot of ICDS for on-treatment samples from the Riaz et al. cohort. P values were computed via a one-sided Wilcoxon rank-sum test. (D) Receiver operating correlation curve and area under the curve of ICD signatures for on-treatment samples from the Riaz et al. cohort. (E, F) Kaplan–Meier curves of PFS and OS for on-treatment samples based on ICD signature scores for the Riaz et al. cohort.

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