Fig. 3
LMK235 attenuated chronic inflammation in the border zone 21 days after MI. A-B, Representative images of HE staining in each group at a magnification of 40×, and statistical analysis of inflammatory infiltration area (n = 3 for each group). C-G, Western blot results and statistical analysis of TNF-α, IL-6, cleaved-IL-1β and pro-IL-1β expression (n = 5 for sham group and sham + LMK235 group, while n = 7 for MI group and MI + LMK235 group). The band of TNF-α, cleaved-IL-1β and GAPDH were from the same gel, and the band of IL-6 and pro-IL-1β were from the other two gels. The data are presented as the mean ± SD, ☨P < 0.05 vs. the sham group, *P < 0.001 vs. the sham group, #P < 0.001 vs. the MI group. The samples derive from the same experiment and that blots were processed in parallel. The original blots are presented in Supplementary Figs. 10–16.
