Fig. 5 | Scientific Reports

Fig. 5

From: GCC2 promotes non-small cell lung cancer progression by maintaining Golgi apparatus integrity and stimulating EGFR signaling pathways

Fig. 5

GCC2 knockdown compromises Golgi apparatus integrity and decreases nuclear translocation of EGFR. Immunofluorescence analysis of (A) GM130 and GCC2 and in H460 and H1299 cells and (B) GM130 in control and GCC2 knockdown H460 and H1299 cells. (C) Western blot analysis of EGFR in control and GCC2 knockdown H460 cells. (D) Immunostaining for EGFR in control or GCC2 knockdown H460 cells; Representative images are shown. Scale bar = 10 μm. Data are presented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Back to article page