Fig. 8 | Scientific Reports

Fig. 8

From: Phosphorylated tau in cerebrospinal fluid-derived extracellular vesicles in Alzheimer’s disease: a pilot study

Fig. 8

P-tau217 in CSF and EVs. (a) Meso Scale Discovery assay of P-tau217 from trapped EVs from the same CSF samples. Aspiration of 75 µl at 200 µl 1/m. EVs were lysed with tween 0.5%. The red dashed line is a low detection limit (twice the lowest value on the calibration standard). A Wilcoxon rank-sum test indicates a statistically significant difference between the groups for both CSF and EVs but with opposite directions. (b) Meso Scale Discovery assay of P-tau217 from CSF of AD (N = 20) and CU (N = 20) samples.

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