Table 1 Cytotoxic activities of compounds 1 and 2 on HCT-116 and HepG2 cancer cell lines.

From: Anticancer, antimicrobial, insecticidal and molecular docking of sarcotrocheliol and cholesterol from the marine soft coral Sarcophyton Trocheliophorum

Cell line name

Conc. (µg/ml)

1

2

Viability %

IC50 (µg/mL)

SI

Viability %

IC50 (µg/mL)

SI

Wi38

100

58.93 ± 0.21

112.5 ± 3.42

--

49 ± 1.0

97.2 ± 2.14

--

50

71.9 ± 0.95

64.33 ± 0.33

25

80.83 ± 0.72

76.86 ± 0.69

12.5

95.23 ± 0.67

90.33 ± 0.88

6.25

99.66 ± 0.33

95 ± 1.0

0

100 ± 0.0

100 ± 0.0

HCT-116

100

21.192 ± 0.2

11.8 ± 1.0

9.53

17.223 ± 0.43

10.4 ± 0.9

9.34

50

24.077 ± 0.63

28.471 ± 0.29

25

38.488 ± 0.86

34.094 ± 0.58

12.5

55.184 ± 1.0

51.845 ± 0.66

6.25

82.073 ± 0.4

72.583 ± 0.55

0

100 ± 0.0

100 ± 0.0

HepG2

100

32.199 ± 0.69

8.8 ± 0.3

12.78

25.817 ± 0.78

12.0 ± 0.4

8.1

50

32.185 ± 0.4

32.358 ± 0.81

25

40.619 ± 0.37

46.471 ± 0.83

12.5

52.323 ± 0.29

55.938 ± 0.52

6.25

78.313 ± 0.78

81.755 ± 0.72

0

100 ± 0.0

100 ± 0.0