Table 6 Association between haplotype and the risk of LAA.

From: EDNRA affects susceptibility to large artery atherosclerosis stroke through potential inflammatory pathway

HapMap block

Haplotype*

Cases Freq

Controls Freq

Adjusted OR (95% CI)

P**

Block 1

CCGGGT

0.6577

0.6705

1.00

/

TAAAGA

0.24

0.2327

1.03 (0.79–1.33)

0.85

CCGACA

0.0859

0.0887

0.96 (0.65–1.42)

0.84

Block 2

AC

0.7033

0.7235

1.00

/

GT

0.2208

0.182

0.91 (0.69–1.19)

0.49

GC

0.0759

0.0945

1.12 (0.76–1.67)

0.56

Block 3

CGT

0.7815

0.811

1.00

/

TAC

0.1156

0.1021

0.90 (0.64–1.28)

0.56

CAC

0.0899

0.0718

0.78 (0.52–1.15)

0.21

Block 4

GA

0.5664

0.5401

1.00

/

CG

0.376

0.3926

1.18 (0.94–1.48)

0.16

CA

0.0539

0.0636

1.13 (0.72–1.78)

0.59

  1. Notes: *Haplotypes with frequency < 1% were omitted, **Adjusted for gender, hypertension, diabetes, heart diseases, smoking status, drinking habits, overweightness, carotid stenosis and HHCY.
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