Fig. 2 | Scientific Reports

Fig. 2

From: Circadian rhythm genes contribute to the prognosis prediction and potential therapeutic target in gastric cancer

Fig. 2

Establishment and evaluation of the circadian rhythm gene signature. (A) Heatmap of differentially expressed CRGs. Blue indicates low expression and red indicates high expression. (B) Adjusted parameter selection in the Lasso Cox model, each curve represents a gene, and the proximity of the y-axis values indicates the corresponding gene coefficients (C) Cross-validation adjusted parameter selection for LASSO regression. (DF) K-M survival curves of the training cohort, testing cohort and validation cohort. p < 0.05 indicates that the difference in survival times between the two groups is statistically significant. (GI) The ROC curves of the training cohort, testing cohort and validation cohort. The larger the AUC, the better the specificity and sensitivity of the signature.

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