Fig. 9

Enrichment analysis and protein–protein interaction networks. (A-B) GSEA enriched pathways in the high- and low-risk group. The X-axis represents genes sorted in order, while the Y-axis indicates the corresponding Running Enrichment Score. The peaks in the line graph correspond to the enrichment scores for this gene set. Different colored curves represent various pathways, and the gray area plot displays the signal noise of the genes. (C-D) GO and KEGG enrichment analyses of DEGs between the between high- and low-risk groups. The size of the bubbles or the length of the bars represents the quantity of enriched genes. (E) Protein–protein interaction networks of DEGs between the high- and low-risk groups. The ellipses represent genes, while the lines indicate the presence of interaction relationships. (F) Hub genes of protein–protein interaction networks. The rectangles represent genes, while the lines indicate the presence of interaction relationships. Blue denotes ordinary genes, while colors represent hub genes.