Fig. 1

Associations between circulating amino acid levels and the presence of coronary artery disease. This rainplot represents the results of the first set of regression, in which metabolites were used as dependent variables (vertical axis), while CAD phenotype (two-level variable opposing sickness vs health) and confounders served as independent variables (horizontal axis). The redder the dots, the higher the β coefficient and the bigger the dot, the smaller the adjusted p-value. Metabolites with similar β coefficients and adjusted p-values were clustered together (left side of the rainplot). BH Benjamini–Hochberg.