Table 4 Cox proportional hazard regression analysis for progression-free survival after propensity score weighting.
Parameter | Univariate Analysis Hazard Ratio (95% CI) | p-Value | Multivariate Analysis Hazard Ratio (95% CI) | p-Value |
---|---|---|---|---|
TACE method 5-Fu-cTACE 5-Fu-DEB-TACE | 1.00 0.57(0.33–0.97) | 0.041 | 1.00 0.59(0.35–0.98) | 0.044 |
Gender | Â | 0.793 | Â | Â |
Female | 1.00 | Â | Â | Â |
Male | 0.92(0.52–1.62) |  |  |  |
Age(years) | 1.01(0.99–1.03) | 0.227 |  |  |
Diabetes No Yes | 1.00 1.39(0.75–2.58) | 0.284 |  |  |
History of HB No Yes | 1.00 1.07(0.64–1.81) | 0.774 |  |  |
Liver Cirrhosis No Yes | 1.00 0.91(0.58–2.02) | 0.790 |  |  |
AFP(µg/L) <400 ≥ 400 | 1.00 0.97(0.52–1.80) | 0.937 |  |  |
PIVKA-II(mAU/ml) <40 ≥ 40 | 1.00 1.61(0.85-3.05) | 0.141 |  |  |
Ascites No Yes | 1.00 2.59(1.51–4.46) | <0.001 | 1.00 2.00(1.01–3.96) | 0.046 |
MELD Low risk Medium risk | 1.00 4.65(3.01–7.19) | <0.001 | 1.00 2.47(1.23–4.93) | 0.010 |
ALBI Level 1 Level 2 | 1.00 1.39(0.80–2.41) | 0.239 |  |  |
Child-pugh Stage A B | 1.00 3.30(1.88–5.80) | <0.001 | 1.00 1.82(0.77–4.32) | 0.17 |
ECOG performance status 0 1 2 | 1.00 1.38(0.71–2.67) 1.04(0.50–2.18) | 0.339 0.905 |  |  |
BCLC Stage A B C | 1.00 2.63(1.19–5.84) 3.16(1.45–6.87) | 0.016 0.003 | 1.00 2.30(1.05–5.02) 3.35(1.56–7.19) | 0.036 0.001 |
Largest nodule size (cm) ≥ 5 <5 | 1.00 1.33(0.72–2.66) | 0.325 |  |  |
Tumor multiplicity Unifocal Multifocal | 1.00 1.25(0.74–2.12) | 0.388 |  |  |
Vascular Invasion No Yes | 1.00 1.78(1.04–3.07) | 0.034 | 1.00 1.48(0.88–2.47) | 0.13 |
Lymphatic Metastasis No Yes | 1.00 1.42(0.84–2.41) | 0.182 |  |  |
Extrahepatic metastasis No Yes | 1.00 1.63(0.93–2.84) | 0.082 |  |  |