Fig. 4
From: Targeted imaging of pulmonary fibrosis by a cyclic peptide LyP-1
LyP-1 selectively accumulates in the fibrotic lung in vivo. Mice were i.v. injected with FITC-labeled ARA or LyP-1 peptides at day 18 after BLM instillation, and major mouse organs were collected at 2 h after peptide injection. (a) Representative fluorescent images of major mouse organs in each group were obtained by a Li-COR Odyssey infrared imaging system. (b) The average fluorescence intensity of FITC in each organ of ARA- or LyP-1-injected control or BLM mice was analyzed. The results are presented as the mean ± SD, n = 7 mice per group. Statistical relevance was determined for each organ by Mann–Whitney test (for lungs), or one-way ANOVA followed by the Bonferroni posttest (for other organs).
