Fig. 1

ROC curve of HbA1c and UACR for the sensitivity and specificity of DPN in patients with T2DM (A) Showed the ROC curve of HbA1c for the sensitivity and specificity of DPN in T2DM patients without DN; the AUC is 0.673; The cut-off point for HbA1c (7.65%) achieved a sensitivity of 86.0% with a specificity of 44.6% in patients without DN. (B) Showed the ROC curve of UACR for the sensitivity and specificity of DPN in T2DM patients with DN; the AUC 0.654; The cut-off point for UACR (196.081Â mg/g) yielded a sensitivity of 52.9% with a specificity of 76.2% in patients with DN. Abbreviations: ROC, receiver operating characteristic; HbA1c, glycosylated hemoglobin; UACR, urinary albumin-to-creatinine ratio; DPN, diabetic peripheral neuropathy; T2DM, type 2 diabetes mellitus; DN, diabetic nephropathy.