Table 4 Severity of multiple symptoms in HT patients and healthy controls.
Symptom | HT Group (n = 108) | Control group (n = 57) | Pa value | Pb value | ||
|---|---|---|---|---|---|---|
M (P25, P75) | Mean (SD) | M (P25, P75) | Mean (SD) | |||
Digestive system | 16 (11, 24) | 18.00 (9.45) | 11 (9, 15) | 12.11 (4.05) | 0.002 | 0.003 |
 Anorexia | 1 (1, 2) | 1.43 (1.46) | 1 (1, 2) | 1.25 (0.59) | 0.649 | 0.565 |
 Abdominal distension | 4 (2, 5) | 3.91 (2.05) | 1 (1, 3) | 1.74 (1.12) |  < 0.001 |  < 0.001 |
 Constipation | 3 (2, 5) | 3.18 (2.11) | 2 (1, 3) | 2.14 (1.65) | 0.015 | 0.029 |
 Diarrhea | 2 (1, 4) | 2.71 (2.21) | 1 (1, 2) | 1.33 (0.91) | 0.004 | 0.003 |
 Gastrointestinal cramps | 1 (1, 2) | 1.43 (1.25) | 1 (1, 1) | 1.37 (1.18) | 0.883 | 0.840 |
 Acid reflux | 1 (1, 2) | 1.93 (1.94) | 1 (1, 1) | 1.40 (1.04) | 0.505 | 0.196 |
 Burning sensation | 1 (1, 1) | 1.68 (1.81) | 1 (1, 1) | 1.11 (0.50) | 0.513 | 0.115 |
 Hiccup | 2 (1, 3) | 2.50 (2.24) | 1 (1, 2) | 1.74 (1.34) | 0.067 | 0.109 |
Respiratory system | 2 (2, 3) | 2.45 (1.63) | 2 (2, 3) | 2.37 (1.47) | 0.926 | 0.838 |
 Cough | 1 (1, 2) | 1.39 (0.97) | 1 (1, 2) | 1.48 (1.25) | 0.857 | 0.724 |
 Asthma | 1 (1, 1) | 1.05 (0.86) | 1 (1, 1) | 0.89 (0.42) | 0.626 | 0.351 |
Circulatory system | 6 (4, 10) | 7.41 (4.62) | 4 (4, 7) | 5.37 (3.53) | 0.024 | 0.046 |
 Bradycardia | 1 (1, 1) | 1.25 (1.37) | 1 (1, 1) | 0.88 (0.58) | 0.293 | 0.192 |
 Palpitations | 1 (1, 3) | 2.20 (1.93) | 1 (1, 3) | 1.96 (1.68) | 0.606 | 0.595 |
 Chest tightness | 2 (1, 3) | 2.34 (1.77) | 1 (1, 2) | 1.57 (1.36) | 0.020 | 0.037 |
 Hypotension | 1 (1, 2) | 1.64 (1.68) | 1 (1, 1) | 1.11 (0.81) | 0.353 | 0.131 |
Endocrine system | 15 (10, 19) | 14.93 (6.55) | 7 (6, 11) | 7.85 (4.32) |  < 0.001 |  < 0.001 |
 Chilliness | 3 (1, 6) | 3.79 (2.65) | 1 (1, 2) | 1.65 (1.32) |  < 0.001 |  < 0.001 |
 Gain weight | 3 (2, 6) | 3.64 (2.69) | 1 (1, 2) | 1.61 (0.89) |  < 0.001 |  < 0.001 |
 Facial edema | 2 (1, 4) | 2.86 (2.25) | 1 (1, 2) | 1.38 (1.02) | 0.001 | 0.002 |
 Weight loss | 1 (1, 1) | 1.04 (0.79) | 1 (1, 1) | 0.92 (0.48) | 0.800 | 0.503 |
 Parched | 1 (1, 3) | 2.21 (2.07) | 1 (1, 2) | 1.50 (1.27) | 0.177 | 0.109 |
 Sweating | 1 (1, 2) | 1.70 (1.53) | 1 (1, 1) | 1.07 (0.79) | 0.049 | 0.057 |
Neuropsychiatric system | 31 (21, 46) | 34.73 (18.94) | 16 (12, 28) | 22.25 (15.77) |  < 0.001 | 0.004 |
 Headache | 2 (1, 3) | 2.27 (1.95) | 1 (1, 3) | 1.63 (1.36) | 0.114 | 0.130 |
 Dizziness | 1 (1, 3) | 2.13 (1.95) | 1 (1, 2) | 1.37 (1.00) | 0.103 | 0.063 |
 Forgetfulness | 3 (3, 6) | 4.21 (2.44) | 1 (1, 2) | 2.07 (1.87) |  < 0.001 |  < 0.001 |
 Anxiety | 3 (2, 5) | 3.84 (2.25) | 2 (1, 4) | 2.77 (2.17 | 0.009 | 0.045 |
 Depressed | 2 (1, 4) | 2.84 (2.07) | 1 (1, 2) | 1.59 (1.67) | 0.001 | 0.008 |
 Fatigue | 4 (3, 6) | 4.41 (2.59) | 2 (2, 4) | 2.96 (1.57) | 0.005 | 0.012 |
 Insomnia | 2 (1, 4) | 2.93 (2.41) | 1 (1, 2) | 1.92 (1.92) | 0.029 | 0.045 |
 Multiple dreams | 2 (1, 5) | 3.30 (2.85) | 1 (1, 3) | 2.22 (2.35) | 0.037 | 0.092 |
 Drowsiness | 2 (1, 4) | 3.07 (2.81) | 1 (1, 2) | 2.33 (2.43) | 0.204 | 0.246 |
 Irritability | 3 (2, 6) | 3.84 (2.81) | 1 (1, 3) | 2.23 (1.75) | 0.007 | 0.009 |
 Indifferent | 1 (1, 4) | 2.50 (2.37) | 1 (1, 1) | 1.34 (1.64) | 0.018 | 0.028 |
Movement system | 5 (4, 10) | 7.46 (5.37) | 4 (4, 6) | 4.55 (3.77) | 0.004 | 0.014 |
 Joint pain | 1 (1, 3) | 2.27 (1.82) | 1 (1, 1) | 1.23 (1.03) | 0.003 | 0.008 |
 Muscle pain | 1 (1, 4) | 2.18 (1.90) | 1 (1, 1) | 1.57 (1.83) | 0.044 | 0.181 |
 Swelling | 1 (1, 2) | 1.91 (1.83) | 1 (1, 1) | 0.96 (0.72) | 0.003 | 0.013 |
 Numbness | 1 (1, 1) | 1.46 (1.51) | 1 (1, 1) | 0.96 (0.52) | 0.088 | 0.104 |
Reproductive system | 4 (2, 5) | 4.86 (4.82) | 4 (3, 5) | 3.92 (2.35) | 0.915 | 0.346 |
 Menorrhagia | 1 (1, 1) | 0.98 (0.90) | 1 (1, 2) | 1.26 (1.07) | 0.162 | 0.212 |
 Oligomenorrhea | 1 (1, 1) | 1.96 (2.53) | 1 (1, 1) | 1.30 (1.46) | 0.642 | 0.223 |
 Infertility | 1 (0, 1) | 1.23 (2.17) | 1 (0, 1) | 0.73 (0.45) | 0.671 | 0.247 |
 Miscarriage | 1 (0, 1) | 0.91 (1.39) | 1 (0, 1) | 0.76 (0.42) | 0.662 | 0.614 |
Mucocutaneous system | 19 (12, 28) | 22.52 (13.58) | 14 (10, 18) | 15.22 (8.71) | 0.008 | 0.013 |
 Dry skin | 2 (1, 6) | 3.52 (2.75) | 1 (1, 3) | 1.84 (1.46) | 0.006 | 0.005 |
 Pruritus | 2 (1, 5) | 3.23 (2.65) | 1 (1, 3) | 2.03 (1.90) | 0.038 | 0.043 |
 Acne | 1 (1, 3) | 2.16 (2.21) | 1 (1, 2) | 1.69 (1.64) | 0.379 | 0.339 |
 Dermatitis | 1 (1, 2) | 1.89 (2.25) | 1 (1, 1) | 1.34 (1.09) | 0.477 | 0.243 |
 Subcutaneous bleeding | 1 (1, 1) | 1.34 (1.60) | 1 (1, 1) | 1.04 (0.82) | 0.539 | 0.369 |
 Mouth ulcers | 1 (1, 2) | 1.79 (1.60) | 1 (1, 2) | 1.80 (1.47) | 0.956 | 0.953 |
 Photosensitivity | 1 (1, 1) | 1.82 (2.19) | 1 (1, 1) | 1.23 (1.03) | 0.420 | 0.196 |
 Hair loss | 3 (1, 5) | 3.34 (2.38) | 1 (1, 3) | 2.03 (1.98) | 0.009 | 0.018 |
 Eyebrows fall out | 1 (1, 3) | 1.82 (1.82) | 1 (1, 1) | 1.15 (0.83) | 0.257 | 0.079 |
 Fragile nails | 1 (1, 3) | 2.48 (2.37) | 1 (1, 2) | 1.61 (1.38) | 0.165 | 0.088 |
