Fig. 1
From: Anesthetic effects on electrophysiological responses across the visual pathway
Scotopic ERG and a-wave Fitting. (A) Representative scotopic and photopic ERG responses in mice treated with different anesthetics. (B) The scotopic and photopic ERG waveforms from different groups were processed with a band-pass filter of 0.3–30 Hz to remove the influence of oscillatory potentials. (C–E) A-wave fitting waveforms for EC (C), AR (D), and PS (E). (F–H) Quantitative statistics of the a-wave related parameters, Rmax (F), S (G), and Td (H), derived from fitting with the Lamb and Pugh model. Representative data are presented as mean ± SEM; n = 6 independent biological replicates. Two-way ANOVA tests with Tukey’s multiple comparisons. *, P < 0.05; **, P < 0.01; ***, P < 0.001. All experiments were independently performed at least three times to ensure repeatable results.
