Fig. 5
From: Anesthetic effects on electrophysiological responses across the visual pathway
Characterization of PERG under varied anesthetic conditions in mice. (A) Schematic of the PERG experiment. (B) The waveforms of PERG results in mice under the influence of three different anesthetics: EC, AR, and PS, are illustrated. (C–D) The implicit times (C) and amplitude (D) for N1, P1, and N2 waves among the groups are quantified. (E–M) Statistical analysis of parameters following frequency-___domain analysis, including magnitude (E–G), phase (H–J), and power spectral density (PSD) (K–M). Compared to the other two groups, the PS group mice (G, J, M) demonstrated insensitivity to graphic stimuli when compared with the EC (E, H, K) and AR (F, I, L) groups. Representative data are presented as mean ± SEM; n = 6 independent biological replicates. Two-way ANOVA tests with Tukey’s multiple com-parisons. *, P < 0.05; **, P < 0.01; ***, P < 0.001. All experiments were independently performed at least three times to ensure repeatable results.
