Fig. 5

Molecular characteristics and functional pathways in different PANoptosis patterns. (A, B) Visual summary showing common genetic alterations in the high and low-PANGPI groups. (C) GSEA plot showing the top 5 pathways in the high-risk group compared to the low-risk group. (D) Forest plot of gene mutations in the patients. (E) Interaction effect of genes mutating differentially in patients. (F) Heatmap displaying the inflammatory response genes expression between high and low-PANGPI groups. *p < 0.05. Heatmap was generated with R software (v. 4.3.1; https://cran.r-project.org/web/packages/pheatmap/index.html).