Fig. 3
From: Jararaca GPIb-binding protein causes thrombocytopenia during Bothrops jararaca envenomation
Representative tracings of platelet aggregation induced by BjV, heated BjV, or ultrafiltration fractions of BjV in washed platelet suspensions from humans or BALB/c mice, or in mouse whole blood. Bovine thrombin (0.1 U/mL, final concentration) or collagen (12 µg/mL, final concentration) were used as positive controls. Aliquots (20 µL) of the fractions (Table 1) were applied to washed platelet suspensions. In the case of aggregation in mouse whole blood, 40 µL of UF50 was applied instead. The asterisk indicates the addition of the corresponding agonist. These results are representative of two different experiments.
