Fig. 7

AKR1C3 modulation of EMT through AKT and JNK/NF-κB pathways. (a) NF-κB phosphorylation stimulated by AKR1C3 knockdown was not inhibited by LY294002 (an AKT inhibitor). (b) NF-κB phosphorylation increase due to AKR1C3 knockdown was counteracted by SP600125 (a JNK inhibitor). *P < 0.05, unpaired t test.