Fig. 3

YPF demonstrated a positive impact on the maturation of DCs. (A–D) DCs in spleen, primary myeloid cells, tumors tissues, and paracancerous tissues. (E) IL-12 secretion of tumor tissues and paracancerous tissues. (F,G) The maturation of mouse bone marrow-derived DCs induced by normal culture medium or tumor supernatant. (H) IL-12 secretion of mouse bone marrow-derived DCs induced by normal culture medium or tumor supernatant. Data are presented as the means ± SD.*P < 0.05 and **P < 0.01 vs. Model group; #P < 0.05 and ##P < 0.01 vs. Control group.